Molecular imaging for the diagnosis of dementia

Nobuyuki Okamura

Research output: Contribution to journalArticlepeer-review


Many radiotracers have been developed to visualize pathological protein accumulation and neurotransmitter deficits in the brains of patients with dementia using positron emission tomography (PET). Recent advances in the development of β-sheet binding agents enabled in vivo detection of senile plaques in Alzheimer's disease. Molecular imaging using these agents would contribute to the early and accurate diagnosis of dementia and monitoring therapeutic effect of anti-dementia drugs.

Original languageEnglish
Pages (from-to)487-495
Number of pages9
JournalJapanese Journal of Clinical Radiology
Issue number4
Publication statusPublished - 2010 Apr 1

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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