Molecular genetics of intraductal papillary-mucinous neoplasms of the pancreas

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13 Citations (Scopus)

Abstract

Intraductal papillary-mucinous neoplasms of the pancreas show characteristic clinicopathological and molecular pathobiological features which are distinct from those of conventional ductal adenocarcinomas. Alterations of KRAS, AKT/PKB, CDKN2A, TP53, SMAD4, STK11/LKB1, and DUSP6, and other molecular alterations, including global expression studies as well as their clinical implications, are discussed.

Original languageEnglish
Pages (from-to)233-237
Number of pages5
JournalJournal of Hepato-Biliary-Pancreatic Surgery
Volume14
Issue number3
DOIs
Publication statusPublished - 2007 May 1
Externally publishedYes

Keywords

  • DUSP6
  • IPMN
  • PanIN
  • Pancreatic cancer
  • SMAD4

ASJC Scopus subject areas

  • Surgery
  • Hepatology

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