Molecular epidemiological analyses of Cryptosporidium parvum virus 1 (CSpV1), a symbiotic virus of Cryptosporidium parvum, in Japan

Fumi Murakoshi, Madoka Ichikawa-Seki, Junya Aita, Seiko Yaita, Aiko Kinami, Katsuhisa Fujimoto, Yoshifumi Nishikawa, Shin Murakami, Taisuke Horimoto, Kentaro Kato

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We show that Cryptosporidium parvum virus 1 (CSpV1), a member of the family Partitiviridae, genus Cryspovirus that can infect Cryptosporidium parvum, is a new candidate for high-resolution tool for tracing C. parvum. CSpV1 was detected in all C. parvum-positive samples tested. Phylogenetic analysis of dsRNA1 sequence from CSpV1 can distinguish infected areas of C. parvum on the national level. Sequences detected in samples from Iwate prefecture and other islands (Tanegashima, and Okinawa) belonged to a single clade. This system can differentiate the samples from Hokkaido and south part of Japan as well as from other countries. Samples from Iwate, Tanegashima, and Okinawa belonged to a single subclade, respectively. Therefore, the CSpV1 dsRNA sequences reflect the regional distribution of their host and have potential as a high-resolution tool to trace C. parvum IIaA15G2R1 subtype.

Original languageEnglish
Pages (from-to)69-72
Number of pages4
JournalVirus Research
Volume211
DOIs
Publication statusPublished - 2016 Jan 4

Keywords

  • Cryprosporidium parvum
  • Cryptosporidium parvum virus 1
  • DsRNA viruses
  • Epidemiology
  • Partitiviridae

ASJC Scopus subject areas

  • Cancer Research
  • Virology
  • Infectious Diseases

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