Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB

Eugene Futai, Tomoteru Kubo, Hiroyuki Sorimachi, Koichi Suzuki, Tatsuya Maeda

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains.

Original languageEnglish
Pages (from-to)316-319
Number of pages4
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1517
Issue number2
DOIs
Publication statusPublished - 2001 Jan 26
Externally publishedYes

Keywords

  • Calpain
  • PalB
  • PalBH
  • Proteolysis

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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