Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: Emergence of CTX-M-15-producing E. coli ST131

Hitoshi Kuroda, Hisakazu Yano, Yoichi Hirakata, Kazuaki Arai, Shiro Endo, Hajime Kanamori, Hiromi Yamamoto, Sadahiro Ichimura, Miho Ogawa, Masahiro Shimojima, Mayumi Komatsu, Teruko Jonai, Sachiko Itagaki, Yuriko Nonomiya, Akira Suwabe, Mitsuo Kaku

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

We investigated the molecular characteristics of ESBL-producing Escherichia coli in Japan. A total of 101 clinical isolates of ESBL-positive E. coli collected in Japan between June 2008 and November 2009 were studied. Among the 101 strains, 97 were positive for CTX-M, while 47 and two were positive for TEM and SHV, respectively. Sequencing revealed that CTX-M-14 was most common (49/101), followed by CTX-M-27 (22/101) and CTX-M-15 (8/101). Based on MLST data, seven of eight CTX-M-15 producers belonged to ST131. This is the first report about clinical isolates of E. coli ST131 possessing CTX-M-15 in Japan.

Original languageEnglish
Pages (from-to)201-203
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume74
Issue number2
DOIs
Publication statusPublished - 2012 Oct

Keywords

  • CTX-M-15
  • ESBLs
  • Escherichia coli

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Molecular characteristics of extended-spectrum β-lactamase-producing Escherichia coli in Japan: Emergence of CTX-M-15-producing E. coli ST131'. Together they form a unique fingerprint.

Cite this