Molecular biology of blood pressure regulatory genes

Kazuhisa Takeuchi

doi:10.1620/tjem.197.1

Molecular biology of blood pressure regulatory genes

Kazuhisa Takeuchi

PHA - Pharmacy

Research output: Contribution to journal › Review article › peer-review

Abstract

Blood pressure is determined by vascular resistance and circulating volume. Activation of vascular angiotensin II or thromboxane receptor is mostly involved in the former, and function of renal prostagalandin EP₃, receptor or thiazide-sensitive sodium-chloride co-transporter is also in the latter. We have cloned rat genes for these blood pressure regulatory factors, and studied their gene expression. Here we review the molecular biology of those genes, based on our observations.

Original language	English
Pages (from-to)	1-8
Number of pages	8
Journal	Tohoku Journal of Experimental Medicine
Volume	197
Issue number	1
DOIs	https://doi.org/10.1620/tjem.197.1
Publication status	Published - 2002 May 1

Keywords

Gitelman's syndrome
HFH-3
NRF-2
PPARγ
Sp-1
Translational medicine

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1620/tjem.197.1

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