To clarify the clinical significance of moderately atypical squamous cells, 7167 males with slightly atypical squamous cells on sputum cytology (group A) and 82 males with moderately atypical squamous cells (group B) were followed for 4 years on average, and risks for cancer development were compared between the two groups. As a result, 87 cases were newly diagnosed as cancer in group A and 2 cases from group B respectively. The cancer incidence per person-year was 274/100,000 in group A and 547.8/100,000 in group B. The relative risk of group B was 1.99 times of group A. However there was no significance in incidence between the two groups. In conclusion, the risk for cancer development in group A is similar to that in group B. This indicates that moderately atypical squamous cell cases should be judged as being cancer free as proposed by the Japan Lung Cancer Committee.
- Lung cancer
- Moderately atypical squamous cells
- Slightly atypical squamous cells
- Sputum cytology
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine