Modeling and numerical simulation of axisymmetric stenosis growth in an artery

Takuji Ishikawa, Shuzo Oshima, Ryiuchiro Yamane

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

There are several hypotheses as to why stenosis appears in an artery. However, there is no accepted theory as yet. In this study, axisy mmetric stenosis growth in an artery is modeled based on three hypotheses; (1) high wall shear stress theory (2) low wall shear stress theory (3) oscillatory shear index theory. In each hypothesis, stenosis growth is simulated numerically. Flow-is assumed to be periodic, incompressible and axisymmetric. Non-Newtonian viscosity of blood and movement of arterial wall are considered. Flow pattern, concentration pattern and distribution of mass flux on the wall are computed. By using these results, stenosis growth process is obtained. It is found that the stenosis growth process based on the high wall shear stress theory is consistent with the clinical case. However, stenosis does not grow so much in the case of the low wall shear stress theory and the oscillatory shear index theory.

Original languageEnglish
Pages (from-to)2982-2989
Number of pages8
JournalNihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
Volume65
Issue number637
DOIs
Publication statusPublished - 1999 Sep
Externally publishedYes

Keywords

  • Bio-fluid mechanics
  • Diffusion
  • Fluid dynamics
  • Non-newtonian fluid
  • Numerical analysis
  • Pulsation

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Mechanical Engineering

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