Model-based prediction of circadian system responses to a heat load pulse

Mitsuyuki Nakao, Tsuyoshi Ichikawa, Dennis McGinty, Ronald Szymusiak, Mitsuaki Yamamoto

Research output: Contribution to journalConference articlepeer-review

Abstract

We developed a thermoregulatory model of sleep control based on the hypothesis that non rapid eye movement sleep participates in the homeostatic thermoregulation. This model successfully reproduced several qualitative features of human sleep-wake cycles. Here, in order to provide an experimentally verifiable prediction concerning behavior of human circadian system, the model response to a heat load pulse was simulated. As a result, the strong phase-dependent responses to the heat load pulse was predicted by the model. This is an intriguing result which deserves to be studied experimentally.

Original languageEnglish
Pages (from-to)1729-1730
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume4
Publication statusPublished - 1996 Dec 1
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 4 (of 5) - Amsterdam, Neth
Duration: 1996 Oct 311996 Nov 3

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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