The mitogenic activities of the whole cells of the 40 strains of Lactobacillus acidophilus group lactic acid bacteria and the cell wall components from selected strains were evaluated by using murine spleen and Peyer's patch cells. The whole cells of many of the strains showed a high mitogenic response. The cell wall of L gasseri LA158 was a B-Cell mitogen. Acidic polysaccharide (APS) and peptidoglycan (PG) isolated from the cell wall of LA158 showed strong mitogenic activity in both cells. No teichoic acids were found in the cell wall of this strain. Both, neutral polysaccharide (NPS) and acidic polysaccharide (APS) consisted of D-glucose (glucan), and the latter contained 1.0% (w/w) phosphorus. The stimulation activity on lymphocytes shown by the whole cells of LA158 was thought to be induced by APS and PG.
|Number of pages||5|
|Publication status||Published - 1997 Dec 1|
ASJC Scopus subject areas
- Food Science