Missense mutation of Abcg5 in stroke-prone spontaneously hypertensive rats does not influence lymphatic sitosterol absorption regardless of the dose: Comparison with Wistar rats

Tadateru Hamada, Yoko Kodama, Katsumi Imaizumi, Ikuo Ikeda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The lymphatic recovery of radiolabeled sitosterol administered in various amounts to the stomach was almost the same between stroke-prone spontaneously hypertensive rats (SHRSPs), a strain having a missense mutation in ATP binding cassette transporter g5 (Abcg5), and Wistar rats, a normal strain. The results suggest that the mutation of Abcg5 in SHRSPs, compared with Wistar rats, did not influence the ability for intestinal sitosterol absorption regardless of the dose.

Original languageEnglish
Pages (from-to)2777-2778
Number of pages2
JournalBioscience, Biotechnology and Biochemistry
Volume73
Issue number12
DOIs
Publication statusPublished - 2009

Keywords

  • ATP binding cassette transporter G5 (Abcg5)
  • ATP binding cassette transporter G8 (ABCG8)
  • Intestinal absorption
  • Plant sterol
  • Stroke-prone spontaneously hypertensive rat (SHRSP)

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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