Minimal multiple liver metastases after chemotherapy from colorectal cancer could be revealed with intra operative ultrasonography using SONAZOID™

Shigeru Ottomo, Toshiki Rikiyama, Shinichi Egawa, Yu Katayose, Fuyuhiko Motoi, Kuniharu Yamamoto, Hiroshi Yoshida, Takayuki Miura, Yuji Funayama, Michiaki Unno

Research output: Contribution to journalArticlepeer-review

Abstract

A 57-year-old man diagnosed with advanced colorectal cancer showing 25 liver metastases not curatively resectable underwent internal sphincteric resection (ISR), then 8 chemotherapy (mFOLFOX6) courses. Thereafter, liver metastases shrank dramatically or disappeared, leaving 5 tumors detected in multi detector-row computed tomography (MDCT) and enhanced magnetic resonance imaging (MRI). In the second surgery, intraoperative ultrasonography using SonazoidTM showed 24 minimal hepatic tumors, necessitating right hepatectomy and left partial hepatic resection leaving no residual tumors. Seven months after hepatectomy, the man shows no sign of recurrence. In conclusion, intraoperative ultrasonography with SonazoidTM is a good modality for detecting minimal liver metastasis.

Original languageEnglish
Pages (from-to)490-496
Number of pages7
JournalJapanese Journal of Gastroenterological Surgery
Volume44
Issue number4
DOIs
Publication statusPublished - 2011

Keywords

  • Colorectal cancer
  • Liver metastasis
  • Sonazoid

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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