In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.
|Number of pages||2|
|Journal||Fertility and sterility|
|Publication status||Published - 2009 Apr|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology