Microtubule organization during human parthenogenesis

Yukihiro Terada, Hisataka Hasegawa, Tomohisa Ugajin, Takashi Murakami, Nobuo Yaegashi, Kunihiro Okamura

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.

Original languageEnglish
Pages (from-to)1271-1272
Number of pages2
JournalFertility and sterility
Volume91
Issue number4
DOIs
Publication statusPublished - 2009 Apr 1

Keywords

  • Parthenogenesis
  • centrosome
  • human
  • microtubules

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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