Microtubule organization during human parthenogenesis

Yukihiro Terada; Hisataka Hasegawa; Tomohisa Ugajin; Takashi Murakami; Nobuo Yaegashi; Kunihiro Okamura

doi:10.1016/j.fertnstert.2008.05.051

Microtubule organization during human parthenogenesis

Yukihiro Terada, Hisataka Hasegawa, Tomohisa Ugajin, Takashi Murakami, Nobuo Yaegashi, Kunihiro Okamura

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.

Original language	English
Pages (from-to)	1271-1272
Number of pages	2
Journal	Fertility and sterility
Volume	91
Issue number	4
DOIs	https://doi.org/10.1016/j.fertnstert.2008.05.051
Publication status	Published - 2009 Apr

Keywords

Parthenogenesis
centrosome
human
microtubules

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynaecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.fertnstert.2008.05.051

Cite this

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title = "Microtubule organization during human parthenogenesis",

abstract = "In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.",

keywords = "Parthenogenesis, centrosome, human, microtubules",

author = "Yukihiro Terada and Hisataka Hasegawa and Tomohisa Ugajin and Takashi Murakami and Nobuo Yaegashi and Kunihiro Okamura",

year = "2009",

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doi = "10.1016/j.fertnstert.2008.05.051",

language = "English",

volume = "91",

pages = "1271--1272",

journal = "Fertility and Sterility",

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TY - JOUR

T1 - Microtubule organization during human parthenogenesis

AU - Terada, Yukihiro

AU - Hasegawa, Hisataka

AU - Ugajin, Tomohisa

AU - Murakami, Takashi

AU - Yaegashi, Nobuo

AU - Okamura, Kunihiro

PY - 2009/4

Y1 - 2009/4

N2 - In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.

AB - In human fertilization, the sperm centrosome plays a crucial role as a microtubule organizing center (MTOC). We studied microtubule organization during human parthenogenesis, which occurs when a human egg undergoes cleavage without a sperm centrosome. Multiple cytoplasmic asters were organized in the human oocyte after parthenogenetic activation, indicating that multiple MTOC are present in the human oocyte cytoplasm and function like a human sperm centrosome during parthenogenesis.

KW - Parthenogenesis

KW - centrosome

KW - human

KW - microtubules

UR - http://www.scopus.com/inward/record.url?scp=62949167165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=62949167165&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2008.05.051

DO - 10.1016/j.fertnstert.2008.05.051

M3 - Article

C2 - 18706544

AN - SCOPUS:62949167165

SN - 0015-0282

VL - 91

SP - 1271

EP - 1272

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 4

ER -

Microtubule organization during human parthenogenesis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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