Microreactor for synthesis via intermediates with assembled units enabling rapid mixing and heat transfer and short residence time

Nobuaki Aoki; Ryouhei Kitajima; Chiharu Itoh; Kazuhiro Mae

Microreactor for synthesis via intermediates with assembled units enabling rapid mixing and heat transfer and short residence time

Nobuaki Aoki, Ryouhei Kitajima, Chiharu Itoh, Kazuhiro Mae

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper describes a reactor for multi-step syntheses via intermediates with improved selectivity of desired products. This reactor is referred as assembled reactor. This reactor consists of mixing, residence time and heat exchange units. It was applied to the synthesis of bromobenzene via p-bromophenyllithium and gave the product yield > 80%. The assemble reactor enabled rapid mixing and heat transfer and short residence time between successive reaction steps and offers a opportunity to be used in multi-step syntheses via unstable intermediates with improved product distribution in industrial production. This is an abstract of a paper presented at the 42nd Loss Prevention Symposium (New Orleans, LA 4/6-10/2008).

Original language	English
Title of host publication	2008 AIChE Spring National Meeting, Conference Proceedings
Publication status	Published - 2008 Dec 23
Event	2008 AIChE Spring National Meeting, Conference - New Orleans, LA, United States Duration: 2008 Apr 6 → 2008 Apr 10

Other

Other	2008 AIChE Spring National Meeting, Conference
Country/Territory	United States
City	New Orleans, LA
Period	08/4/6 → 08/4/10

Keywords

Assembled units
Heat transfer
Mixing
Residence Time
Synthesis via intermediates

ASJC Scopus subject areas

Biotechnology
Chemical Engineering(all)
Bioengineering
Safety, Risk, Reliability and Quality

Cite this

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title = "Microreactor for synthesis via intermediates with assembled units enabling rapid mixing and heat transfer and short residence time",

abstract = "This paper describes a reactor for multi-step syntheses via intermediates with improved selectivity of desired products. This reactor is referred as assembled reactor. This reactor consists of mixing, residence time and heat exchange units. It was applied to the synthesis of bromobenzene via p-bromophenyllithium and gave the product yield > 80%. The assemble reactor enabled rapid mixing and heat transfer and short residence time between successive reaction steps and offers a opportunity to be used in multi-step syntheses via unstable intermediates with improved product distribution in industrial production. This is an abstract of a paper presented at the 42nd Loss Prevention Symposium (New Orleans, LA 4/6-10/2008).",

keywords = "Assembled units, Heat transfer, Mixing, Residence Time, Synthesis via intermediates",

author = "Nobuaki Aoki and Ryouhei Kitajima and Chiharu Itoh and Kazuhiro Mae",

year = "2008",

month = dec,

day = "23",

language = "English",

isbn = "9780816910236",

booktitle = "2008 AIChE Spring National Meeting, Conference Proceedings",

note = "2008 AIChE Spring National Meeting, Conference ; Conference date: 06-04-2008 Through 10-04-2008",

}

TY - GEN

T1 - Microreactor for synthesis via intermediates with assembled units enabling rapid mixing and heat transfer and short residence time

AU - Aoki, Nobuaki

AU - Kitajima, Ryouhei

AU - Itoh, Chiharu

AU - Mae, Kazuhiro

PY - 2008/12/23

Y1 - 2008/12/23

N2 - This paper describes a reactor for multi-step syntheses via intermediates with improved selectivity of desired products. This reactor is referred as assembled reactor. This reactor consists of mixing, residence time and heat exchange units. It was applied to the synthesis of bromobenzene via p-bromophenyllithium and gave the product yield > 80%. The assemble reactor enabled rapid mixing and heat transfer and short residence time between successive reaction steps and offers a opportunity to be used in multi-step syntheses via unstable intermediates with improved product distribution in industrial production. This is an abstract of a paper presented at the 42nd Loss Prevention Symposium (New Orleans, LA 4/6-10/2008).

AB - This paper describes a reactor for multi-step syntheses via intermediates with improved selectivity of desired products. This reactor is referred as assembled reactor. This reactor consists of mixing, residence time and heat exchange units. It was applied to the synthesis of bromobenzene via p-bromophenyllithium and gave the product yield > 80%. The assemble reactor enabled rapid mixing and heat transfer and short residence time between successive reaction steps and offers a opportunity to be used in multi-step syntheses via unstable intermediates with improved product distribution in industrial production. This is an abstract of a paper presented at the 42nd Loss Prevention Symposium (New Orleans, LA 4/6-10/2008).

KW - Assembled units

KW - Heat transfer

KW - Mixing

KW - Residence Time

KW - Synthesis via intermediates

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UR - http://www.scopus.com/inward/citedby.url?scp=57749103297&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:57749103297

SN - 9780816910236

BT - 2008 AIChE Spring National Meeting, Conference Proceedings

T2 - 2008 AIChE Spring National Meeting, Conference

Y2 - 6 April 2008 through 10 April 2008

ER -

Microreactor for synthesis via intermediates with assembled units enabling rapid mixing and heat transfer and short residence time

Abstract

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Keywords

ASJC Scopus subject areas

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