Micropatterns of protein molecules were fabricated by a method based on anodic oxidation of Si surface by atomic force microscope (AFM). In this method, an arbitrary pattern of oxide is drawn on the Si surface by applying a voltage between the conducting AFM probe and the Si substrate. The oxide pattern is then used as a template for immobilization of protein molecules. The obtained patterns were investigated with AFM and scanning electron microscope (SEM).
- Anodic Oxidation
- Atomic Force Microscope (AFM)
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