Micro/nanoelectrochemical probe and chip devices for evaluation of three-dimensional cultured cells

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Herein, we present an overview of recent research progress in the development of micro/nanoelectrochemical probe and chip devices for the evaluation of three-dimensional (3D) cultured cells. First, we discuss probe devices: a general outline, evaluation of O2 consumption, enzyme-modified electrodes, evaluation of endogenous enzyme activity, and the collection of cell components from cell aggregates are discussed. The next section is focused on integrated chip devices: a general outline, electrode array devices, smart electrode array devices, droplet detection of 3D cultured cells, cell manipulation using dielectrophoresis (DEP), and electrodeposited hydrogels used for fabrication of 3D cultured cells on chip devices are discussed. Finally, we provide a summary and discussion of future directions of research in this field.

Original languageEnglish
Pages (from-to)4343-4354
Number of pages12
JournalAnalyst
Volume142
Issue number23
DOIs
Publication statusPublished - 2017 Dec 7

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

Fingerprint Dive into the research topics of 'Micro/nanoelectrochemical probe and chip devices for evaluation of three-dimensional cultured cells'. Together they form a unique fingerprint.

  • Cite this