Micro/nano-patterned surfaces for control of cell adhesion and cell functions: Differentiation into adipocytes

Makiko Goto, Kae Sato, Takehiko Tsukahara, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

Cell adhesion surfaces having micro/nano patterns and controlled chemical properties were fabricated. The patterning at a subcellular-scale should control the formation of focal adhesion formation that plays an important role in many cellular functions. We observed that preadipocytes adhered, proliferated on the surfaces, and were induced to differentiate. Individual cells adhered and grew on the patterns but confluent cell monolayers on nano patterns easily detached from the substrata. The micro/nano patterns provide cells with unique scaffolds controlling cell-matrix interactions at a subcellular scale.

Original languageEnglish
Pages993-995
Number of pages3
Publication statusPublished - 2006 Jan 1
Externally publishedYes
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: 2006 Nov 52006 Nov 9

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
CountryJapan
CityTokyo
Period06/11/506/11/9

Keywords

  • Cell adhesion
  • Cell differentiation
  • Nano patterning

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Goto, M., Sato, K., Tsukahara, T., Konno, T., Ishihara, K., & Kitamori, T. (2006). Micro/nano-patterned surfaces for control of cell adhesion and cell functions: Differentiation into adipocytes. 993-995. Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.