Micro-phase-contrast X-ray computed tomography for basic biomëdical research in SPrine-8

Jin Wu; Tbhoru Takeda; Thet Thet Lwin; Ichiro Koyama; Atsushi Momose; Akiko Fujii; Yoshitaka Hamaishi; Taichi Kuroe; Tetsuya Yuasa; Yoshio Suzuki; Takao Akatsuka

doi:10.1117/12.559390

Micro-phase-contrast X-ray computed tomography for basic biomëdical research in SPrine-8

Jin Wu, Tbhoru Takeda, Thet Thet Lwin, Ichiro Koyama, Atsushi Momose, Akiko Fujii, Yoshitaka Hamaishi, Taichi Kuroe, Tetsuya Yuasa, Yoshio Suzuki, Takao Akatsuka

Research output: Contribution to journal › Conference article › peer-review

7 Citations (Scopus)

Abstract

Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.

Original language	English
Article number	85
Pages (from-to)	740-747
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5535
DOIs	https://doi.org/10.1117/12.559390
Publication status	Published - 2004 Dec 1
Externally published	Yes
Event	Developments in X-Ray Tomography IV - Denver, CO, United States Duration: 2004 Aug 4 → 2004 Aug 6

Keywords

3D medical image
Biomedical object
Interferometer
Micro-phase-contrast X-ray CT
Synchrotron radiation

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.559390

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title = "Micro-phase-contrast X-ray computed tomography for basic biom{\"e}dical research in SPrine-8",

abstract = "Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.",

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author = "Jin Wu and Tbhoru Takeda and Lwin, {Thet Thet} and Ichiro Koyama and Atsushi Momose and Akiko Fujii and Yoshitaka Hamaishi and Taichi Kuroe and Tetsuya Yuasa and Yoshio Suzuki and Takao Akatsuka",

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AU - Wu, Jin

AU - Takeda, Tbhoru

AU - Lwin, Thet Thet

AU - Koyama, Ichiro

AU - Momose, Atsushi

AU - Fujii, Akiko

AU - Hamaishi, Yoshitaka

AU - Kuroe, Taichi

AU - Yuasa, Tetsuya

AU - Suzuki, Yoshio

AU - Akatsuka, Takao

PY - 2004/12/1

Y1 - 2004/12/1

N2 - Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.

AB - Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.

KW - 3D medical image

KW - Biomedical object

KW - Interferometer

KW - Micro-phase-contrast X-ray CT

KW - Synchrotron radiation

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JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

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ER -

Micro-phase-contrast X-ray computed tomography for basic biomëdical research in SPrine-8

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Keywords

ASJC Scopus subject areas

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