Abstract
Micro-phase-contrast X-ray computed tomography with an X-ray interferometer (micro-phase-contrast CT) is in operation to obtain high spatial resolution images of less than 0.01 mm at the undulator beam-line 20XU of SPring-8, Japan, and we applied micro-phase-contrast CT to observe the organs of rats and hamsters. The excised kidney and spleen fixed by formalin were imaged. The fine inner-structures such as vessels, glomeruli of kidney and white and red pulps of spleen were visualized clearly about 0.01-mm spatial resolutions without using contrast agent or staining procedure. The results were very similar to those by optical microscopic images with 20-fold magnification. These results suggest that the micro-phase tomography might be a useful tool for various biomedical researches.
Original language | English |
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Article number | 85 |
Pages (from-to) | 740-747 |
Number of pages | 8 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 5535 |
DOIs | |
Publication status | Published - 2004 Dec 1 |
Externally published | Yes |
Event | Developments in X-Ray Tomography IV - Denver, CO, United States Duration: 2004 Aug 4 → 2004 Aug 6 |
Keywords
- 3D medical image
- Biomedical object
- Interferometer
- Micro-phase-contrast X-ray CT
- Synchrotron radiation
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering