TY - JOUR
T1 - Micro-multiphase laminar flows for the extraction and detection of carbaryl derivative
AU - Smirnova, Adelina
AU - Mawatari, Kazuma
AU - Hibara, Akihide
AU - Proskurnin, Mikhail A.
AU - Kitamori, Takehiko
N1 - Funding Information:
This research was partially supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan.
PY - 2006/2/3
Y1 - 2006/2/3
N2 - A new solvent extraction concentration method utilizing microchip technology has been developed. As an important application of this system, carbaryl determination with thermal lens microscope detection was demonstrated. Carbaryl pesticide was hydrolyzed in an alkaline medium to 1-naphthol, was coupled with diazotized trimethylaniline, and, then, was extracted to toluene as a colored azo dye. Two microchips with modified complex-shape microchannels were used for mixing, reaction, extraction, and detection. A thermal lens microscope was used for the detection of the colored product. Optimum conditions for aqueous phase and organic phase flow rates inside the microchannels were identified. The calibration line indicated good linearity for concentrations of 3.4 × 10-7 to 3.5 × 10-6 M and a detection limit of 7 × 10-8 M was obtained. This limit of detection is at least two orders less than LODs for conventional spectrophotometric methods. The results with the present integrated system suggested there was a good potential for implementing an on-site carbaryl analysis system.
AB - A new solvent extraction concentration method utilizing microchip technology has been developed. As an important application of this system, carbaryl determination with thermal lens microscope detection was demonstrated. Carbaryl pesticide was hydrolyzed in an alkaline medium to 1-naphthol, was coupled with diazotized trimethylaniline, and, then, was extracted to toluene as a colored azo dye. Two microchips with modified complex-shape microchannels were used for mixing, reaction, extraction, and detection. A thermal lens microscope was used for the detection of the colored product. Optimum conditions for aqueous phase and organic phase flow rates inside the microchannels were identified. The calibration line indicated good linearity for concentrations of 3.4 × 10-7 to 3.5 × 10-6 M and a detection limit of 7 × 10-8 M was obtained. This limit of detection is at least two orders less than LODs for conventional spectrophotometric methods. The results with the present integrated system suggested there was a good potential for implementing an on-site carbaryl analysis system.
KW - Carbaryl
KW - Liquid-liquid interface
KW - Microchip
KW - Solvent extraction
KW - Thermal lens microscopy
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U2 - 10.1016/j.aca.2005.10.073
DO - 10.1016/j.aca.2005.10.073
M3 - Article
AN - SCOPUS:31044434528
VL - 558
SP - 69
EP - 74
JO - Analytica Chimica Acta
JF - Analytica Chimica Acta
SN - 0003-2670
IS - 1-2
ER -