Micro-flow visualization of magnetic nanoparticles for biomedical applications

R. Lima, R. J. Joseyphus, T. Ishikawa, Y. Imai, T. Yamaguchi

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

An investigation to measure the flow behavior of magnetic nanoparticles through a 100? m microchannel is conducted. The magnetic field is applied externally by a permanent magnet and by using a micro-PTV system it was possible to measure the flow behavior of magnetic nanoparticles at different flow rates and magnetic fields through a 100?m glass capillary. A strong dependence on both magnetic and hydrodynamic force is observed on the nanoparticles fluidic paths. Based on these in vitro studies, important parameters and issues that require further understanding and investigation are point out.

Original languageEnglish
Title of host publicationSingle and Two-Phase Flows on Chemical and Biomedical Engineering
PublisherBentham Science Publishers Ltd.
Pages600-612
Number of pages13
ISBN (Print)9781608053476
DOIs
Publication statusPublished - 2012

Keywords

  • Bioseparation
  • Blood
  • Cancer therapy
  • Drug delivery
  • Feoxide layer
  • Glass capillary
  • Hyperthermia
  • MRI contrast agent
  • Magnetic nanoparticles
  • Micro-PIV/PTV
  • Micro/nano flow
  • Microchannel
  • Microcirculation
  • Physiological fluid
  • Superparamagnetism

ASJC Scopus subject areas

  • Engineering(all)

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