Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

R. L. Schnaar; A. Yamamoto; K. Furukawa; S. Yamashiro; M. Shin; M. Okada; S. Fukumoto; M. Haraguchi; N. Takeda; K. Fujimura; M. Sakae; M. Kishikawa; H. Shiku; K. Furukawa; S. Aizawa

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

R. L. Schnaar, A. Yamamoto, K. Furukawa, S. Yamashiro, M. Shin, M. Okada, S. Fukumoto, M. Haraguchi, N. Takeda, K. Fujimura, M. Sakae, M. Kishikawa, H. Shiku, K. Furukawa, S. Aizawa

Research output: Contribution to journal › Review article › peer-review

Abstract

Mice genetically engineered to lack complex brain gangliosides developed normal brain anatomy, histology, and ultrastructure, although they demonstrated a modest change in central nervous system conduction velocity.

Original language	English
Pages (from-to)	195-200
Number of pages	6
Journal	Chemtracts
Volume	11
Issue number	3
Publication status	Published - 1998 Mar
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)
Biochemistry
Molecular Biology

Cite this

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. / Schnaar, R. L.; Yamamoto, A.; Furukawa, K.; Yamashiro, S.; Shin, M.; Okada, M.; Fukumoto, S.; Haraguchi, M.; Takeda, N.; Fujimura, K.; Sakae, M.; Kishikawa, M.; Shiku, H.; Furukawa, K.; Aizawa, S.

In: Chemtracts, Vol. 11, No. 3, 03.1998, p. 195-200.

Research output: Contribution to journal › Review article › peer-review

Schnaar, R. L. ; Yamamoto, A. ; Furukawa, K. ; Yamashiro, S. ; Shin, M. ; Okada, M. ; Fukumoto, S. ; Haraguchi, M. ; Takeda, N. ; Fujimura, K. ; Sakae, M. ; Kishikawa, M. ; Shiku, H. ; Furukawa, K. ; Aizawa, S. / Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. In: Chemtracts. 1998 ; Vol. 11, No. 3. pp. 195-200.

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title = "Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system",

abstract = "Mice genetically engineered to lack complex brain gangliosides developed normal brain anatomy, histology, and ultrastructure, although they demonstrated a modest change in central nervous system conduction velocity.",

author = "Schnaar, {R. L.} and A. Yamamoto and K. Furukawa and S. Yamashiro and M. Shin and M. Okada and S. Fukumoto and M. Haraguchi and N. Takeda and K. Fujimura and M. Sakae and M. Kishikawa and H. Shiku and K. Furukawa and S. Aizawa",

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AU - Schnaar, R. L.

AU - Yamamoto, A.

AU - Furukawa, K.

AU - Yamashiro, S.

AU - Shin, M.

AU - Okada, M.

AU - Fukumoto, S.

AU - Haraguchi, M.

AU - Takeda, N.

AU - Fujimura, K.

AU - Sakae, M.

AU - Kishikawa, M.

AU - Shiku, H.

AU - Furukawa, K.

AU - Aizawa, S.

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Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

Abstract

ASJC Scopus subject areas

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