Metallic glass nanofibers in future hydrogel-based scaffolds

Ramin Banan Sadeghian, Samad Ahadian, Shin Yaginuma, Javier Ramon-Azcon, Xiaobin Liang, Ken Nakajima, Hitoshi Shiku, Tomokazu Matsue, Koji S. Nakayama, Ali Khademhosseini

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Electrically conductive reinforced hydrogels offer a wide range of applications as three-dimensional scaffolds in tissue engineering. We report electrical and mechanical characterization of methacrylated gelatin (GelMA) hydrogel, containing palladium-based metallic glass nanofibers (MGNF). Also we show that the fibers are biocompatible and C2C12 myoblasts in particular, planted into the hybrid hydrogel, tend to attach to and elongate along the fibers. The MGNFs in this work were created by gas atomization. Ravel of fibers were embedded in the GelMA prepolymer in two different concentrations (0.5 and 1.0 mg/ml), and then the ensemble was cured under UV light, forming the hybrid hydrogel. The conductivity of the hybrid hydrogel was proportional to the fiber concentration.

Original languageEnglish
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages5276-5279
Number of pages4
ISBN (Electronic)9781424479290
DOIs
Publication statusPublished - 2014 Nov 2
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: 2014 Aug 262014 Aug 30

Publication series

Name2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period14/8/2614/8/30

Keywords

  • Conductive hydrogel scaffolds
  • Metallic glass nanofibers
  • Methacrylated gelatin

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering
  • Medicine(all)

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