TY - JOUR
T1 - Mesoporous calcium phosphate via post-treatment of α-TCP
AU - Kitamura, Makoto
AU - Ohtsuki, Chikara
AU - Ogata, Shin Ichi
AU - Kamitakahara, Masanobu
AU - Tanihara, Masao
AU - Miyazaki, Toshiki
PY - 2005/4/1
Y1 - 2005/4/1
N2 - α-Tricalcium phosphate (α-TCP) macroporous ceramic scaffold was chemically treated with a buffered solution at pH = 4. Mesopores were formed in the scaffold after the treatment to result in a remarkable increase in surface area of the scaffold. The increase in the surface area is caused by precipitation of octacalcium phosphate (OCP). Bimodal pore size distribution consisting of mesopores and macropores obtained by the treatment of α-TCP scaffold having higher initial porosity brought about high adsorption of bovine serum albumin (BSA) than monomodal pore size distribution of mesopores. Adsorption of BSA, acidic protein, was suggested to result from crystallographic characters of OCP.
AB - α-Tricalcium phosphate (α-TCP) macroporous ceramic scaffold was chemically treated with a buffered solution at pH = 4. Mesopores were formed in the scaffold after the treatment to result in a remarkable increase in surface area of the scaffold. The increase in the surface area is caused by precipitation of octacalcium phosphate (OCP). Bimodal pore size distribution consisting of mesopores and macropores obtained by the treatment of α-TCP scaffold having higher initial porosity brought about high adsorption of bovine serum albumin (BSA) than monomodal pore size distribution of mesopores. Adsorption of BSA, acidic protein, was suggested to result from crystallographic characters of OCP.
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U2 - 10.1111/j.1551-2916.2005.00164.x
DO - 10.1111/j.1551-2916.2005.00164.x
M3 - Article
AN - SCOPUS:27644514524
VL - 88
SP - 822
EP - 826
JO - Journal of the American Ceramic Society
JF - Journal of the American Ceramic Society
SN - 0002-7820
IS - 4
ER -