Mesoporous calcium phosphate via post-treatment of α-TCP

Makoto Kitamura; Chikara Ohtsuki; Shin Ichi Ogata; Masanobu Kamitakahara; Masao Tanihara; Toshiki Miyazaki

doi:10.1111/j.1551-2916.2005.00164.x

Mesoporous calcium phosphate via post-treatment of α-TCP

Makoto Kitamura, Chikara Ohtsuki, Shin Ichi Ogata, Masanobu Kamitakahara, Masao Tanihara, Toshiki Miyazaki

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

α-Tricalcium phosphate (α-TCP) macroporous ceramic scaffold was chemically treated with a buffered solution at pH = 4. Mesopores were formed in the scaffold after the treatment to result in a remarkable increase in surface area of the scaffold. The increase in the surface area is caused by precipitation of octacalcium phosphate (OCP). Bimodal pore size distribution consisting of mesopores and macropores obtained by the treatment of α-TCP scaffold having higher initial porosity brought about high adsorption of bovine serum albumin (BSA) than monomodal pore size distribution of mesopores. Adsorption of BSA, acidic protein, was suggested to result from crystallographic characters of OCP.

Original language	English
Pages (from-to)	822-826
Number of pages	5
Journal	Journal of the American Ceramic Society
Volume	88
Issue number	4
DOIs	https://doi.org/10.1111/j.1551-2916.2005.00164.x
Publication status	Published - 2005 Apr 1
Externally published	Yes

ASJC Scopus subject areas

Ceramics and Composites
Materials Chemistry

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title = "Mesoporous calcium phosphate via post-treatment of α-TCP",

abstract = "α-Tricalcium phosphate (α-TCP) macroporous ceramic scaffold was chemically treated with a buffered solution at pH = 4. Mesopores were formed in the scaffold after the treatment to result in a remarkable increase in surface area of the scaffold. The increase in the surface area is caused by precipitation of octacalcium phosphate (OCP). Bimodal pore size distribution consisting of mesopores and macropores obtained by the treatment of α-TCP scaffold having higher initial porosity brought about high adsorption of bovine serum albumin (BSA) than monomodal pore size distribution of mesopores. Adsorption of BSA, acidic protein, was suggested to result from crystallographic characters of OCP.",

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T1 - Mesoporous calcium phosphate via post-treatment of α-TCP

AU - Kitamura, Makoto

AU - Ohtsuki, Chikara

AU - Ogata, Shin Ichi

AU - Kamitakahara, Masanobu

AU - Tanihara, Masao

AU - Miyazaki, Toshiki

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AB - α-Tricalcium phosphate (α-TCP) macroporous ceramic scaffold was chemically treated with a buffered solution at pH = 4. Mesopores were formed in the scaffold after the treatment to result in a remarkable increase in surface area of the scaffold. The increase in the surface area is caused by precipitation of octacalcium phosphate (OCP). Bimodal pore size distribution consisting of mesopores and macropores obtained by the treatment of α-TCP scaffold having higher initial porosity brought about high adsorption of bovine serum albumin (BSA) than monomodal pore size distribution of mesopores. Adsorption of BSA, acidic protein, was suggested to result from crystallographic characters of OCP.

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