Mechanical test method on the estimation of the lubricant performance by hyaluronic acid

A. Toshimitsu Yokobori, Takashi Kawaharada, Shigeru Sasaki, Soubei Watanabe, Shou Heng Fang, Shuichi Komatsu, Toshihiro Hayashi

    Research output: Contribution to journalArticlepeer-review

    8 Citations (Scopus)


    Cases with loss of articular cartilage or lowering of articular lubricant performance are frequent among patients afflicted by various gonarthropathies or those fitted with prosthetic joints. The management of such cases has necessitated evaluation studies on the clinical efficacy of using high molecular weight hyaluronic acid as an artificial synovial fluid with a view to improving articular lubricant performance. The proper implementation of such evaluation studies on lubrication performance requires testing methods capable of assessing basic lubricant performance not ouly with respect to articular cartilage alone but also with respect to various other combinations of materials, i.e., lubrication between articular bone and artificial joints, etc. In the present study, first, a simple standard lubricant performance test using several small readily procurable test specimens was devised. Then, this test was employed to evaluate the basic lubricant properties of hyaluronic acidintended for use as artificial synovial fluid.

    Original languageEnglish
    Pages (from-to)117-124
    Number of pages8
    JournalBio-medical materials and engineering
    Issue number2
    Publication statusPublished - 1995 Jan 1


    • Hyaluronic acid
    • Lubrication
    • Mechanical testing
    • Molecular weight
    • Pendulum type friction tester
    • Skeletal joint
    • Viscosity

    ASJC Scopus subject areas

    • Biomaterials
    • Biomedical Engineering


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