Mechanical characterization system of cyanobacteria using a robot integrated microdluidic chip

Takayuki Hasegawa, Shinya Sakuma, Kei Nanatani, Nobuyuki Uozumi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Cyanobacteria have ion channels which response to osmolarity change in living environment. Since it may lead to the mechanical characteristics changes of the cell itself due to the intracellular pressure changes, we focus on constructing the mechanical characteristics measurement system of Synechocystis sp. PCC 6803, one of unicellular cyanobacteria. There are two important issues in constructing the system. Because of features of the cyanobacteria, which is a kind of floating cell whose diameter is a few micrometer, one is how to transport the cell to the measurement point. The other is how to deform the target cell. In this paper, we propose the system combining optical tweezers for transportation of the target cell with the robot integrated microfluidic chip (robochip). The robochip contains an on-chip probe actuated by an external actuator, and a force sensor. We present the concept of the total system, and demonstrated the results of mechanical characterization of a single cyanobacteria.

Original languageEnglish
Title of host publicationIROS Hamburg 2015 - Conference Digest
Subtitle of host publicationIEEE/RSJ International Conference on Intelligent Robots and Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages6033-6038
Number of pages6
ISBN (Electronic)9781479999941
DOIs
Publication statusPublished - 2015 Dec 11
EventIEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015 - Hamburg, Germany
Duration: 2015 Sep 282015 Oct 2

Publication series

NameIEEE International Conference on Intelligent Robots and Systems
Volume2015-December
ISSN (Print)2153-0858
ISSN (Electronic)2153-0866

Other

OtherIEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2015
CountryGermany
CityHamburg
Period15/9/2815/10/2

Keywords

  • Etching
  • Force
  • Force sensors
  • Optical device fabrication
  • Optical sensors
  • Probes
  • System-on-chip

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

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  • Cite this

    Hasegawa, T., Sakuma, S., Nanatani, K., Uozumi, N., & Arai, F. (2015). Mechanical characterization system of cyanobacteria using a robot integrated microdluidic chip. In IROS Hamburg 2015 - Conference Digest: IEEE/RSJ International Conference on Intelligent Robots and Systems (pp. 6033-6038). [7354236] (IEEE International Conference on Intelligent Robots and Systems; Vol. 2015-December). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IROS.2015.7354236