Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip

Di Chang; Shinya Sakuma; Chihiro Uehara; Nobuyuki Uozumi; Fumihito Arai

doi:10.1109/MHS.2018.8886914

Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip

Di Chang, Shinya Sakuma, Chihiro Uehara, Nobuyuki Uozumi, Fumihito Arai

ENG - Biomolecular Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper reports the evaluation results of Young's modulus of single Yeast cell (BY4741). We compared the Young's modulus of wild type and mutant type (ΔCCW12) using our constructed system. The system consists of a robot integrated microfluidic chip and a microscope with an optical tweezers system. The Young's modulus is measured by compressing the cell and measuring cellular reactive force. We succeeded in measuring wild type cells and mutant cells and compared their difference.

Original language	English
Title of host publication	MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781538667927
DOIs	https://doi.org/10.1109/MHS.2018.8886914
Publication status	Published - 2018 Dec
Event	29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018 - Nagoya, Japan Duration: 2018 Dec 10 → 2018 Dec 12

Publication series

Name	MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science

Conference

Conference	29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018
Country/Territory	Japan
City	Nagoya
Period	18/12/10 → 18/12/12

ASJC Scopus subject areas

Human-Computer Interaction
Artificial Intelligence
Electrical and Electronic Engineering
Mechanical Engineering
Control and Optimization
Instrumentation

Access to Document

10.1109/MHS.2018.8886914

Cite this

Chang, D., Sakuma, S., Uehara, C., Uozumi, N., & Arai, F. (2018). Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip. In MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science [8886914] (MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2018.8886914

Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip. / Chang, Di; Sakuma, Shinya; Uehara, Chihiro; Uozumi, Nobuyuki; Arai, Fumihito.

MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science. Institute of Electrical and Electronics Engineers Inc., 2018. 8886914 (MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chang, D, Sakuma, S, Uehara, C, Uozumi, N & Arai, F 2018, Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip. in MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science., 8886914, MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science, Institute of Electrical and Electronics Engineers Inc., 29th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2018, Nagoya, Japan, 18/12/10. https://doi.org/10.1109/MHS.2018.8886914

Chang D, Sakuma S, Uehara C, Uozumi N, Arai F. Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip. In MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science. Institute of Electrical and Electronics Engineers Inc. 2018. 8886914. (MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science). https://doi.org/10.1109/MHS.2018.8886914

Chang, Di ; Sakuma, Shinya ; Uehara, Chihiro ; Uozumi, Nobuyuki ; Arai, Fumihito. / Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip. MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science. Institute of Electrical and Electronics Engineers Inc., 2018. (MHS 2018 - 2018 29th International Symposium on Micro-NanoMechatronics and Human Science).

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title = "Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip",

abstract = "This paper reports the evaluation results of Young's modulus of single Yeast cell (BY4741). We compared the Young's modulus of wild type and mutant type (ΔCCW12) using our constructed system. The system consists of a robot integrated microfluidic chip and a microscope with an optical tweezers system. The Young's modulus is measured by compressing the cell and measuring cellular reactive force. We succeeded in measuring wild type cells and mutant cells and compared their difference.",

author = "Di Chang and Shinya Sakuma and Chihiro Uehara and Nobuyuki Uozumi and Fumihito Arai",

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AB - This paper reports the evaluation results of Young's modulus of single Yeast cell (BY4741). We compared the Young's modulus of wild type and mutant type (ΔCCW12) using our constructed system. The system consists of a robot integrated microfluidic chip and a microscope with an optical tweezers system. The Young's modulus is measured by compressing the cell and measuring cellular reactive force. We succeeded in measuring wild type cells and mutant cells and compared their difference.

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Mechanical Characterization of a Single Yeast Cell Using a Robot Integrated Microfluidic Chip

Abstract

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