Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation

Naoyuki Takeuchi; Katsunori Ikoma; Takayo Chuma; Yuichiro Matsuo

doi:10.1080/02699050600909771

Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation

Naoyuki Takeuchi, Katsunori Ikoma, Takayo Chuma, Yuichiro Matsuo

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20 Citations (Scopus)

Abstract

Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). Research design: Case-control study. Methods and procedures: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). Main outcome and results: The amount of TCI was significantly lower in the patients than the control subjects (p = 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787 p < 0.001). Conclusion: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.

Original language	English
Pages (from-to)	991-996
Number of pages	6
Journal	Brain Injury
Volume	20
Issue number	9
DOIs	https://doi.org/10.1080/02699050600909771
Publication status	Published - 2006 Aug

Keywords

Corpus callosum
Diffuse axonal injury
Transcranial magnetic stimulation
Traumatic brain injury

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Developmental and Educational Psychology
Clinical Neurology

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10.1080/02699050600909771

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title = "Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation",

abstract = "Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). Research design: Case-control study. Methods and procedures: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). Main outcome and results: The amount of TCI was significantly lower in the patients than the control subjects (p = 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787 p < 0.001). Conclusion: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.",

keywords = "Corpus callosum, Diffuse axonal injury, Transcranial magnetic stimulation, Traumatic brain injury",

author = "Naoyuki Takeuchi and Katsunori Ikoma and Takayo Chuma and Yuichiro Matsuo",

note = "Funding Information: We thank Professor Yukio Mano at the Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine for supervision and expertise. We also thank Mami Onodera for technical support. This work was supported by research project grant-in-aid for scientific research No. 16500330 from the Japan Society for the Promotion of Science.",

year = "2006",

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doi = "10.1080/02699050600909771",

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AU - Takeuchi, Naoyuki

AU - Ikoma, Katsunori

AU - Chuma, Takayo

AU - Matsuo, Yuichiro

N1 - Funding Information: We thank Professor Yukio Mano at the Department of Rehabilitation Medicine, Hokkaido University Graduate School of Medicine for supervision and expertise. We also thank Mami Onodera for technical support. This work was supported by research project grant-in-aid for scientific research No. 16500330 from the Japan Society for the Promotion of Science.

PY - 2006/8

Y1 - 2006/8

N2 - Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). Research design: Case-control study. Methods and procedures: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). Main outcome and results: The amount of TCI was significantly lower in the patients than the control subjects (p = 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787 p < 0.001). Conclusion: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.

AB - Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). Research design: Case-control study. Methods and procedures: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). Main outcome and results: The amount of TCI was significantly lower in the patients than the control subjects (p = 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787 p < 0.001). Conclusion: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.

KW - Corpus callosum

KW - Diffuse axonal injury

KW - Transcranial magnetic stimulation

KW - Traumatic brain injury

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Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation

Abstract

Keywords

ASJC Scopus subject areas

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