Measurement of transcallosal inhibition in traumatic brain injury by transcranial magnetic stimulation

Naoyuki Takeuchi, Katsunori Ikoma, Takayo Chuma, Yuichiro Matsuo

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Primary objective: To study whether transcallosal inhibition (TCI) can evaluate the severity of traumatic brain injury (TBI). Research design: Case-control study. Methods and procedures: Twenty patients with a chronic TBI and 20 control subjects were studied. The following transcranial magnetic stimulation parameters were checked; resting motor threshold, central motor latency times, onset latency of TCI, duration of TCI, transcallosal conduction times and amount of TCI. The severity of TBI was evaluated using the Glasgow Coma Scale (GCS). Main outcome and results: The amount of TCI was significantly lower in the patients than the control subjects (p = 0.001). The amount of TCI was highly correlated with the GCS (r = 0.787 p < 0.001). Conclusion: An assessment of TCI was found to be a more sensitive and useful method for an evaluation of the severity of TBI.

Original languageEnglish
Pages (from-to)991-996
Number of pages6
JournalBrain Injury
Volume20
Issue number9
DOIs
Publication statusPublished - 2006 Aug

Keywords

  • Corpus callosum
  • Diffuse axonal injury
  • Transcranial magnetic stimulation
  • Traumatic brain injury

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Developmental and Educational Psychology
  • Clinical Neurology

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