Measurement of internal diameter changes and pulse wave velocity in fetal descending aorta using the ultrasonic phased-tracking method in normal and growth-restricted fetuses

Susumu Miyashita, Jun Murotsuki, Jin Muromoto, Katsusuke Ozawa, Nobuo Yaegashi, Hideyuki Hasegawa, Hiroshi Kanai

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Phased tracking (PT) is an ultrasound-based technique that enables precise measurement of a target velocity. The aims of this study were to use PT to evaluate arterial pulse waveform, pulse wave velocity and fetal pulse pressure in normal and growth-restricted fetuses. One hundred fetuses with normal development and 15 fetuses with growth restriction were analyzed. Ultrasonic raw radiofrequency signals were captured from a direction perpendicular to the vascular axis at the fetal diaphragmatic level for the difference in internal dimensions (DID), or simultaneously from different directions for the pulse wave velocity. Pulsatile movement of the proximal and distal intima of the vessels was analyzed using PT. The fetal DID exhibited no significant changes in growth-restricted fetuses. Pulse wave velocity (3.8 ± 0.32 m/s vs. 2.2 ± 0.069 m/s, p < 0.001) and estimated pulse pressure (6.9 ± 0.90 kPa vs. 2.5 ± 0.18 kPa, p < 0.001) were significantly elevated in growth-restricted fetuses. Assessment of DID and pulse wave velocity of the descending aorta using PT is a feasible, non-invasive approach to evaluation of fetal hemodynamics.

Original languageEnglish
Pages (from-to)1311-1319
Number of pages9
JournalUltrasound in Medicine and Biology
Volume41
Issue number5
DOIs
Publication statusPublished - 2015 May 1

Keywords

  • Fetal growth restriction
  • Fetal pulse pressure
  • Phased-tracking method
  • Pulse wave velocity

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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