Measurement and uniformization of power distribution on the prism for biomedical applications of mid-infrared, attenuated-total-reflection spectroscopy

T. Koyama, S. Kino, T. Sasaki, Y. Wada, R. Kasahara, Y. Oba, Y. Matsuura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To obtain uniform power distribution on the ATR prism for biomedical spectroscopy system, the power intensity mapping on the prism is precisely measured by using a newly developed probing technique. It is found that the distribution of QCL based system is less uniform than that of the FT-IR based system due to the high coherency of the laser beam. To homogenize the distribution, a lens is introduced to diffuse the light and the incident beam is inclined to increase the number of reflections in the prism. As a result, we confirmed that the measurement error of in-vivo experiments is suppressed.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI
EditorsIsrael Gannot, Katy Roodenko
PublisherSPIE
ISBN (Electronic)9781510641051
DOIs
Publication statusPublished - 2021
EventOptical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI 2021 - Virtual, Online, United States
Duration: 2021 Mar 62021 Mar 11

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11635
ISSN (Print)1605-7422

Conference

ConferenceOptical Fibers and Sensors for Medical Diagnostics, Treatment and Environmental Applications XXI 2021
Country/TerritoryUnited States
CityVirtual, Online
Period21/3/621/3/11

Keywords

  • ATR spectroscopy
  • Hollow optical fiber
  • Quantum cascade laser

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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