Mass Screening for Neuroblastoma in Miyagi Prefecture

Masayuki Itano, Sei Morita, Hiromi Fujie, Yoshiyuki Ohashi, Naoko Minegishi, Masayoshi Minegishi, Yoshiko Yamaguchi, Tetsuo Sato, Shigeru Tsuchiya, Tasuke Konno, Yutaka Hayashi, Ryoji Ohi, Hiroyuki Shiraishi

Research output: Contribution to journalArticlepeer-review

Abstract

In Japan, aiming at early and preclinical detection of neuroblastoma in infancy a mass screening program for the tumor has been implemented nationwide using urinary tests for catecholamine metabolites, vanillylmandelic acid (VMA) and homovanillic acid (HVA) (Sawada 1990; Sawada et al. 1991). In this report, the results obtained from the screening program in Miyagi Prefecture for the last 6 years are described. The detection rate of neuroblastoma by mass screening was 1: 8,377 among 125,652 infants tested in Miyagi Prefecture. All but one patients survived after removal of the primary tumor and none or minimal chemotherapy.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalTohoku Journal of Experimental Medicine
Volume168
Issue number2
DOIs
Publication statusPublished - 1992

Keywords

  • mass screening
  • neuroblastoma
  • urine HVA
  • urine VMA

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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