Mapping the phase diagram of DNA hydrogels with droplet microfluidics

Guilhem Mariette, Nicolas Lobato-Dauzier, Robin Deteix, Mia Zhang, Shu Okumura, Yusuke Sato, Masahiro Takinoue, Teruo Fujii, Anthony J. Genot

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

DNA hydrogels have emerged in the recent decade as a powerful substrate to program soft matter at the nanoscale. In particular, DNA hydrogels exhibit liquid/liquid phase separation in vitro, a phenomenon that is appearing to be ubiquitous in cells. Yet, a quantitative understanding of their physics is missing. Here we use a droplet microfluidics platform to prepare tens of thousands of droplets with DNA motifs inside.

Original languageEnglish
Title of host publicationMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages266-267
Number of pages2
ISBN (Electronic)9781733419017
Publication statusPublished - 2020
Event24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
Duration: 2020 Oct 42020 Oct 9

Publication series

NameMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period20/10/420/10/9

Keywords

  • DNA Hydrogels
  • Droplet Microfluidics
  • Phase Separation
  • Temperature Gradient

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering
  • Chemistry(all)
  • Control and Systems Engineering

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