The biological roles of asparagine-linked oligosaccharides (N-glycans) on glycoproteins are thought to take place through the interaction of terminal glycan structures and their receptors. The diversity and avidity of the terminal structures, however, are regulated by the core structure of N-glycans (Schachter 1991). In vertebrates from fish to avian, a pentaantennary N-glycan with a bisecting GlcNAc residue is the most highly branched core structure (Fig. 23.1). Pentaantennary N-glycans were found in hen ovomucoid (Parente et al. 1982; Yamashita et al. 1982) and fish egg glycoproteins (Taguchi et al. 1994, 1995).
|Title of host publication||Handbook of Glycosyltransferases and Related Genes, Second Edition|
|Number of pages||7|
|Publication status||Published - 2014 Jan 1|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)