Management of patients who had undergone non-curative endoscopic submucosal dissection (ESD)/endoscopic mucosal resection (EMR) for early gastric cancer

Waku Hatta, Takuji Gotoda, Tsuneo Oyama, Tomoyuki Koike, Atsushi Masamune, Tooru Shimosegawa

Research output: Contribution to journalArticlepeer-review

Abstract

According to the guidelines established by the Japanese Gastric Cancer Association and Japan Gastroenterological Endoscopy Society, radical surgery is recommended for all patients who underwent non-curative endoscopic submucosal dissection (ESD)/endoscopic mucosal resection (EMR) for early gastric cancer (EGC) because of the potential risk of lymph node metastasis (LNM). However, 29-70% of patients who underwent non-curative ESD/EMR have been followed up with no additional treatment. In addition, the rate of LNM among patients who underwent radical surgery after non-curative ESD/EMR is 4-11% . The strongest independent risk factor for LNM in patients who underwent non-curative ESD is lymphatic invasion, and there are other independent risk factors such as venous invasion as well. We previously reported a simple scoring system for predicting LNM in patients who underwent non-curative ESD, which may provide useful information in clinical practice. Meanwhile, patients with gastric cancer have become older. Thus, the establishment of a prognostic model for predicting overall survival including cancer-related mortality in elderly patients who underwent non-curative ESD/EMR is required.

Original languageEnglish
Pages (from-to)1173-1185
Number of pages13
JournalGASTROENTEROLOGICAL ENDOSCOPY
Volume60
Issue number6
Publication statusPublished - 2018 Jun

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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