Malignant melanoma of the head and neck: A multi-institutional retrospective analysis of cases in Northern Japan

Kiyoto Shiga, Takenori Ogawa, Toshimitsu Kobayashi, Seigo Ueda, Atsushi Kondo, Atsushi Nanba, Shigeru Kuwashima, Yukinori Asada, Seigo Suzuki, Tatsumi Nagahashi, Masafumi Takahashi, Masahiro Suzuki, Akihiro Ishida, Kenichi Watanabe, Yasuaki Harabuchi, Tetsuo Himi, Hideichi Sinkawa, Hiroaki Sato, Shigeru Saijo, Satoshi FukudaKatsuhiko Tanaka, Kazuo Ishikawa, Koichi Omori, Masaru Aoyagi, Sho Hashimoto

Research output: Contribution to journalReview articlepeer-review

30 Citations (Scopus)


Background. Mucosal melanoma of the head and neck is rare and is associated with a poor prognoses because of locoregional failure and distant metastasis. The aim of our study was to review the characteristics of these patients in northern Japan and to analyze their outcomes. Methods. The medical records of 94 patients who had been provided initial treatment in 12 institutes from 1998 to 2007 were reviewed. Results. When the 5-year overall survival rates of patients were evaluated, we found that the survival rates of patients treated by chemotherapy were significantly lower than those of patients treated by surgery or radiation. The survival rates of the single-treatment modality, 2-modality, and ≥3-modality groups were 23.4%, 38.0%, and 33.6%, respectively. Conclusion. Our results suggest that patients who underwent combined treatment had better prognoses. However, we found that chemotherapy had no additional survival benefits.

Original languageEnglish
Pages (from-to)1537-1541
Number of pages5
JournalHead and Neck
Issue number11
Publication statusPublished - 2012 Nov


  • Northern Japan
  • head and neck
  • malignant melanoma
  • prognosis
  • treatment modality

ASJC Scopus subject areas

  • Otorhinolaryngology


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