Male-specific expression of the Fruitless protein is not common to all Drosophila species

Daisuke Yamamoto, Kazue Usui-Aoki, Seigo Shima

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Sex-specific behavioral patterns must be a result of sexual differences in the structure and/or function of the central nervous system (CNS). Male Drosophila melanogaster mutants for the fruitless (fru) locus exhibit enhanced male-to-male courtship. The fru mutant males are accompanied by malformation of the male-specific muscle of Lawrence (MOL), which, in wild-type males, is induced by male motoneurons innervating it. These two phenotypes are the consequences of impaired sex determination of CNS neurons. In D. melanogaster, although the fru mRNAs are transcribed in the CNS of both the male and female, the Fru protein is only translated in the male CNS. This male-specific translation of Fru was also observed in D. simulans, D. yakuba, D. pseudoobscura and D. virilis; however, in D. suzukii, the Fru protein expression was detected even in the female CNS.

Original languageEnglish
Pages (from-to)267-272
Number of pages6
JournalGenetica
Volume120
Issue number1-3
DOIs
Publication statusPublished - 2004 Mar
Externally publishedYes

Keywords

  • Central nervous system
  • Fruitless
  • Sex determination
  • Transformer
  • Translational control

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Genetics
  • Plant Science
  • Insect Science

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