TY - JOUR
T1 - Male-specific expression of the Fruitless protein is not common to all Drosophila species
AU - Yamamoto, Daisuke
AU - Usui-Aoki, Kazue
AU - Shima, Seigo
N1 - Funding Information:
D.Y. would like to thank Prof Jean-Marc Jallon for his invitation to Universite Paris XI, where this manuscript was prepared. The work presented here is in part supported by Special Cooperation Funds for Promoting Science and Technology from Ministry of Education, Culture, Sports, Science and Technology to D.Y. and Waseda University grant number 2000B-029.
PY - 2004/3
Y1 - 2004/3
N2 - Sex-specific behavioral patterns must be a result of sexual differences in the structure and/or function of the central nervous system (CNS). Male Drosophila melanogaster mutants for the fruitless (fru) locus exhibit enhanced male-to-male courtship. The fru mutant males are accompanied by malformation of the male-specific muscle of Lawrence (MOL), which, in wild-type males, is induced by male motoneurons innervating it. These two phenotypes are the consequences of impaired sex determination of CNS neurons. In D. melanogaster, although the fru mRNAs are transcribed in the CNS of both the male and female, the Fru protein is only translated in the male CNS. This male-specific translation of Fru was also observed in D. simulans, D. yakuba, D. pseudoobscura and D. virilis; however, in D. suzukii, the Fru protein expression was detected even in the female CNS.
AB - Sex-specific behavioral patterns must be a result of sexual differences in the structure and/or function of the central nervous system (CNS). Male Drosophila melanogaster mutants for the fruitless (fru) locus exhibit enhanced male-to-male courtship. The fru mutant males are accompanied by malformation of the male-specific muscle of Lawrence (MOL), which, in wild-type males, is induced by male motoneurons innervating it. These two phenotypes are the consequences of impaired sex determination of CNS neurons. In D. melanogaster, although the fru mRNAs are transcribed in the CNS of both the male and female, the Fru protein is only translated in the male CNS. This male-specific translation of Fru was also observed in D. simulans, D. yakuba, D. pseudoobscura and D. virilis; however, in D. suzukii, the Fru protein expression was detected even in the female CNS.
KW - Central nervous system
KW - Fruitless
KW - Sex determination
KW - Transformer
KW - Translational control
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U2 - 10.1023/B:GENE.0000017648.15038.84
DO - 10.1023/B:GENE.0000017648.15038.84
M3 - Article
C2 - 15088665
AN - SCOPUS:1842432107
VL - 120
SP - 267
EP - 272
JO - Genetica
JF - Genetica
SN - 0016-6707
IS - 1-3
ER -