Magnetic biosensor technologies for medical applications: A review

J. Llandro, J. J. Palfreyman, A. Ionescu, C. H.W. Barnes

Research output: Contribution to journalReview article

130 Citations (Scopus)

Abstract

In this review we discuss conventional methods of performing biological assays and molecular identification and highlight their advantages and limitations. An alternative approach based on magnetic nanotechnology is then presented. Firstly, magnetic carriers are introduced and their biocompatibility and functionalisation discussed, with spotlights on functionalisation via self assembled monolayers and on methods of reducing nonspecific binding. In addition an introduction is provided to the basic physical concepts behind the various types of sensors used to detect magnetic labels. Finally, progress in the field of magnetic biosensors and the outlook for the future are discussed.

Original languageEnglish
Pages (from-to)977-998
Number of pages22
JournalMedical and Biological Engineering and Computing
Volume48
Issue number10
DOIs
Publication statusPublished - 2010 Oct 1
Externally publishedYes

Keywords

  • Biomedicine
  • Functionalisation
  • Magnetic biosensors
  • Magnetic nanoparticles

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

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