Magnesium increases calcium absorption mediated by transcellular transport in small intestine of goats and rats

T. Kozakai, K. Katoh, Y. Obara

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    1 Citation (Scopus)

    Abstract

    The effect of an increase in mucosal Mg concentration on Ca absorption mediated by transcellular transport in the stripped epithelia of caprine ileum and rat jejunum was studied. In Ussing chamber experiments, mucosal to serosal flux of Ca (Jms) at 60 mM MgCl2 was significantly (P<0.05) greater than that of control (1.2 mM) in the absence of electrochemical gradient in goats and rats. Furthermore, Mg-induced Jms was significantly decreased (P<0.05) after pre-incubation with thapsigargin. It is concluded that Mg stimulates Ca absorption mediated by transcellular transport, which contributed to the Ca store of endoplasmic reticulum.

    Original languageEnglish
    Pages (from-to)277-280
    Number of pages4
    JournalJournal of Animal and Feed Sciences
    Volume13
    Issue numberSUPPL. 1
    DOIs
    Publication statusPublished - 2004

    Keywords

    • Calcium absorption
    • Intestinal epithelia
    • Magnesium
    • Transcellular pathway

    ASJC Scopus subject areas

    • Food Science
    • Animal Science and Zoology

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