Lung transplantation: present international status and basic approach

K. Shimada, Takashi Kondo, Y. Matsumura, Y. Okada, S. Fujimura

Research output: Contribution to journalArticlepeer-review


Lung transplantation has been established as an optional treatment for irreversible diffuse lung disease. To date, more than 8,000 patients have undergone lung transplantation, while heart-lung transplantation is confined to a very limited number of cases due to the severe shortage of donors. There are various problems in clinical lung transplantation, including limited preservation time, post-transplantation edema, acute and chronic rejection, and a shortage of donor organs. Several solutions to these problems have been found in recent experimental studies. For example, potential therapies for posttransplantation edema have been proposed, and the possibility of long-term preservation has been suggested. Research on xenotransplantation and cadaveric lung transplantation is ongoing, and this may result in options to solve the problem of the shortage of donor organs. In particular, we believe that cadaveric lung transplantation has the potential to become a clinically useful therapy in the near future.

Original languageEnglish
Pages (from-to)759-764
Number of pages6
JournalNippon Geka Gakkai zasshi
Issue number11
Publication statusPublished - 1998 Nov

ASJC Scopus subject areas

  • Medicine(all)


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