Low-valent iron-catalyzed C-C bond formation-addition, substitution, and C-H bond activation

Eiichi Nakamura, Naohiko Yoshikai

Research output: Contribution to journalArticlepeer-review

403 Citations (Scopus)

Abstract

Figure presented. The use of iron as a catalyst for organic synthesis has been increasingly attracting the interest of chemists from economical and ecological points of view. While Fe(III) and Fe(II) catalysts have long been used as Lewis acids for synthesis, we have been interested in exploration of catalysis based on rather unexplored organoiron chemistry since the late 1990s. This Perspective summarizes a series of iron-catalyzed C-C bond formation reactions developed by us, which include (asymmetric) carbometalation of olefins, cross-coupling of alkyl halides, and activation of sp2 and sp3 C-H bonds.

Original languageEnglish
Pages (from-to)6061-6067
Number of pages7
JournalJournal of Organic Chemistry
Volume75
Issue number18
DOIs
Publication statusPublished - 2010 Sep 17
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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