Low temperature synthesis of hydroxyapatite from CaHPO4·2H2O and Ca(OH)2 based on effect of the spark plasma system (SPS)

Mamoru Omori; Takamasa Onoki; Toshiyuki Hashida; Akira Okubo; Yoshihiro Murakami

doi:10.1016/j.ceramint.2005.04.021

Low temperature synthesis of hydroxyapatite from CaHPO₄·2H₂O and Ca(OH)₂ based on effect of the spark plasma system (SPS)

Mamoru Omori, Takamasa Onoki, Toshiyuki Hashida, Akira Okubo, Yoshihiro Murakami

ENG - Fracture and Reliability Research Institute

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

A mixture of 6 mol of CaHPO₄·2H₂O and 4 mol of Ca(OH)₂ was reacted to produce hydroxyapatite (HA) by spark plasma system (SPS). The reaction was carried out at 300-1200 °C under pressure of 20-670 MPa for 10 min in a vacuum. HA formation started at 300 °C at 600 MPa and was completed at 500 °C at 670 MPa, the same product being obtained at 1200 °C in air using a furnace. The temperature of the HA formation increased with decreasing pressure and was 1150 °C under 20 MPa. There was a linear relationship between the reaction temperature and pressure. The crystal size of the HA prepared at 500 °C at 670 MPa and that at 600 °C at 600 MPa by SPS were less than 1 and 2 μm, respectively.

Original language	English
Pages (from-to)	617-621
Number of pages	5
Journal	Ceramics International
Volume	32
Issue number	6
DOIs	https://doi.org/10.1016/j.ceramint.2005.04.021
Publication status	Published - 2006

Keywords

Calcium phosphate
Hydroxyapatite
Hydroxyapatite synthesis
Spark plasma sintering (SPS)
Spark plasma system (SPS)

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Process Chemistry and Technology
Surfaces, Coatings and Films
Materials Chemistry

Access to Document

10.1016/j.ceramint.2005.04.021

Cite this

@article{3d70a6ff663f412f868ab41cd6ed115d,

title = "Low temperature synthesis of hydroxyapatite from CaHPO4·2H2O and Ca(OH)2 based on effect of the spark plasma system (SPS)",

abstract = "A mixture of 6 mol of CaHPO4·2H2O and 4 mol of Ca(OH)2 was reacted to produce hydroxyapatite (HA) by spark plasma system (SPS). The reaction was carried out at 300-1200 °C under pressure of 20-670 MPa for 10 min in a vacuum. HA formation started at 300 °C at 600 MPa and was completed at 500 °C at 670 MPa, the same product being obtained at 1200 °C in air using a furnace. The temperature of the HA formation increased with decreasing pressure and was 1150 °C under 20 MPa. There was a linear relationship between the reaction temperature and pressure. The crystal size of the HA prepared at 500 °C at 670 MPa and that at 600 °C at 600 MPa by SPS were less than 1 and 2 μm, respectively.",

keywords = "Calcium phosphate, Hydroxyapatite, Hydroxyapatite synthesis, Spark plasma sintering (SPS), Spark plasma system (SPS)",

author = "Mamoru Omori and Takamasa Onoki and Toshiyuki Hashida and Akira Okubo and Yoshihiro Murakami",

note = "Funding Information: This study was supported by Research on Advanced Medical Technology in Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan. The authors are thankful to Mr. Shun Ito (Institute for Materials Research, Tohoku University) for transmission electron microscope, observations.",

year = "2006",

doi = "10.1016/j.ceramint.2005.04.021",

language = "English",

volume = "32",

pages = "617--621",

journal = "Ceramics International",

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publisher = "Elsevier Limited",

number = "6",

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T1 - Low temperature synthesis of hydroxyapatite from CaHPO4·2H2O and Ca(OH)2 based on effect of the spark plasma system (SPS)

AU - Omori, Mamoru

AU - Onoki, Takamasa

AU - Hashida, Toshiyuki

AU - Okubo, Akira

AU - Murakami, Yoshihiro

N1 - Funding Information: This study was supported by Research on Advanced Medical Technology in Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan. The authors are thankful to Mr. Shun Ito (Institute for Materials Research, Tohoku University) for transmission electron microscope, observations.

PY - 2006

Y1 - 2006

N2 - A mixture of 6 mol of CaHPO4·2H2O and 4 mol of Ca(OH)2 was reacted to produce hydroxyapatite (HA) by spark plasma system (SPS). The reaction was carried out at 300-1200 °C under pressure of 20-670 MPa for 10 min in a vacuum. HA formation started at 300 °C at 600 MPa and was completed at 500 °C at 670 MPa, the same product being obtained at 1200 °C in air using a furnace. The temperature of the HA formation increased with decreasing pressure and was 1150 °C under 20 MPa. There was a linear relationship between the reaction temperature and pressure. The crystal size of the HA prepared at 500 °C at 670 MPa and that at 600 °C at 600 MPa by SPS were less than 1 and 2 μm, respectively.

AB - A mixture of 6 mol of CaHPO4·2H2O and 4 mol of Ca(OH)2 was reacted to produce hydroxyapatite (HA) by spark plasma system (SPS). The reaction was carried out at 300-1200 °C under pressure of 20-670 MPa for 10 min in a vacuum. HA formation started at 300 °C at 600 MPa and was completed at 500 °C at 670 MPa, the same product being obtained at 1200 °C in air using a furnace. The temperature of the HA formation increased with decreasing pressure and was 1150 °C under 20 MPa. There was a linear relationship between the reaction temperature and pressure. The crystal size of the HA prepared at 500 °C at 670 MPa and that at 600 °C at 600 MPa by SPS were less than 1 and 2 μm, respectively.

KW - Calcium phosphate

KW - Hydroxyapatite

KW - Hydroxyapatite synthesis

KW - Spark plasma sintering (SPS)

KW - Spark plasma system (SPS)

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JO - Ceramics International

JF - Ceramics International

SN - 0272-8842

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