Long-term prognosis of patients with myocardial infarction type 1 and type 2 with and without involvement of coronary vasospasm

J-MINUET investigators

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

While prognoses in relation to myocardial infarction (MI) type have been elucidated in past reports, the results were not consistent, perhaps due to occurrence of Type 2 MI with CVS and its mortality. The Japanese registry of acute Myocardial Infarction diagnosed by Universal Definition (J-MINUET) is a prospective multicenter registry in Japan. In contrast to thromboembolic event-related Type 1 myocardial infarction (MI), clinical features of Type 2 MI, including coronary vasospasm (CVS), are varied due to the heterogeneous nature of its development. To elucidate the MI type-related all-cause mortality, 2989 consecutive patients with AMI were stratified as Type 1 MI, Type 2 MI with CVS, and Type 2 MI with non-CVS. Most patients (n = 2834; 94.8%) were classified as Type 1 MI and 155 patients (5.2%) were classified as Type 2 MI. Of the Type 2 MI patients, 87 (56% of Type 2 MI) were diagnosed as MI with CVS. Although the 3-year mortality was comparable between Type 1 and Type 2 MI patients, significant differences were observed between Type 2 MI with CVS and with non-CVS (3.4% and 22.1%, p < 0.001). Among Japanese patients with AMI, mortality rates between Type 1 MI and Type 2 MI are comparable, but further stratification of Type 2 MI (with or without CVS) may be useful in predicting the prognosis of patients with Type 2 MI.

Original languageEnglish
Article number1686
JournalJournal of Clinical Medicine
Volume9
Issue number6
DOIs
Publication statusPublished - 2020 Jun
Externally publishedYes

Keywords

  • Acute myocardial infarction
  • Clinical outcomes
  • Coronary vasospasm
  • Universal definition of myocardial infarction

ASJC Scopus subject areas

  • Medicine(all)

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