Long Term Complete Remission in Primary Plasma Cell Leukemia

Reiko Tsuyuoka, Kazuwa Nakao, Takayuki Takahashi, Yutaka Sasaki, Kishiko Nakamura, Manabu Fukumoto, Yoshitaka Kurisu, Kumiko Tsubakimori, Kouichi Shioi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


A 76-year-old female was diagnosed as having primary plasma cell leukemia (PCL), based on abundant atypical plasma cells in the circulation and bone marrow, monoclonal k light chain in the serum and urine, the immunophenotype of the plasma cells and the lack of preceding multiple myeloma. The patient was treated with melphalan and prednisolone (MP), and complete remission (CR) was achieved; this was maintained for 28 months. The duration of CR in this patient appears to be the longest of those reported in well-documented primary PCL patients who have been treated with MP chemotherapy. (Internal Medicine 34: 251-254, 1995).

Original languageEnglish
Pages (from-to)251-254
Number of pages4
JournalInternal Medicine
Issue number4
Publication statusPublished - 1995
Externally publishedYes


  • melphalan
  • prednisolone

ASJC Scopus subject areas

  • Internal Medicine


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