Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats

Mutsuo Kudo, Sachiko Saito, Yuji Owada, Harumi Suzaki, Hisatake Kondo

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)172-177
Number of pages6
JournalMolecular Brain Research
Volume75
Issue number1
DOIs
Publication statusPublished - 2000 Jan 10

Keywords

  • Brain
  • In situ hybridization histochemistry
  • Rat
  • SHIP

ASJC Scopus subject areas

  • Molecular Biology
  • Cellular and Molecular Neuroscience

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