TY - JOUR
T1 - Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine
AU - Suzuki, Ryoji
AU - Nourani, Mohammad Reza
AU - Saino-Saito, Sachiko
AU - Abe, Hiroshi
AU - Nochi, Tomonori
AU - Kiyono, Hiroshi
AU - Spener, Friedrich
AU - Kondo, Hisatake
AU - Owada, Yuji
PY - 2009/12
Y1 - 2009/12
N2 - Fatty acid binding protein of epidermal type (E-FABP) was expressed/localized in most, if not all, populations of the dendritic cells in the subepithelial domes, follicles and interfollicular regions of Peyer's patches and presumptive macrophages in their germinal centers, and all M cells in the follicle-associated epithelium of mouse intestine. The immunoreactivity in both of the cell populations makes it easy to recognize the accumulation of DCs in the subepithelial domes in close proximity to the base of M cells, which is essential for luminal antigens to be transported to Peyer's patches. E-FABP may play some important roles in the mucosal immune reaction through Peyer's patches and associated structures.
AB - Fatty acid binding protein of epidermal type (E-FABP) was expressed/localized in most, if not all, populations of the dendritic cells in the subepithelial domes, follicles and interfollicular regions of Peyer's patches and presumptive macrophages in their germinal centers, and all M cells in the follicle-associated epithelium of mouse intestine. The immunoreactivity in both of the cell populations makes it easy to recognize the accumulation of DCs in the subepithelial domes in close proximity to the base of M cells, which is essential for luminal antigens to be transported to Peyer's patches. E-FABP may play some important roles in the mucosal immune reaction through Peyer's patches and associated structures.
KW - Dendritic cells
KW - E-FABP
KW - Immunohistochemistry
KW - M cells
KW - Mouse
KW - Peyer's patch
UR - http://www.scopus.com/inward/record.url?scp=71349086398&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71349086398&partnerID=8YFLogxK
U2 - 10.1007/s00418-009-0638-5
DO - 10.1007/s00418-009-0638-5
M3 - Article
C2 - 19787366
AN - SCOPUS:71349086398
VL - 132
SP - 577
EP - 584
JO - Zeitschrift für Zellforschung und Mikroskopische Anatomie. Abteilung Histochemie
JF - Zeitschrift für Zellforschung und Mikroskopische Anatomie. Abteilung Histochemie
SN - 0948-6143
IS - 6
ER -