Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine

Ryoji Suzuki; Mohammad Reza Nourani; Sachiko Saino-Saito; Hiroshi Abe; Tomonori Nochi; Hiroshi Kiyono; Friedrich Spener; Hisatake Kondo; Yuji Owada

doi:10.1007/s00418-009-0638-5

Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine

Ryoji Suzuki, Mohammad Reza Nourani, Sachiko Saino-Saito, Hiroshi Abe, Tomonori Nochi, Hiroshi Kiyono, Friedrich Spener, Hisatake Kondo, Yuji Owada

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Fatty acid binding protein of epidermal type (E-FABP) was expressed/localized in most, if not all, populations of the dendritic cells in the subepithelial domes, follicles and interfollicular regions of Peyer's patches and presumptive macrophages in their germinal centers, and all M cells in the follicle-associated epithelium of mouse intestine. The immunoreactivity in both of the cell populations makes it easy to recognize the accumulation of DCs in the subepithelial domes in close proximity to the base of M cells, which is essential for luminal antigens to be transported to Peyer's patches. E-FABP may play some important roles in the mucosal immune reaction through Peyer's patches and associated structures.

Original language	English
Pages (from-to)	577-584
Number of pages	8
Journal	Histochemistry and Cell Biology
Volume	132
Issue number	6
DOIs	https://doi.org/10.1007/s00418-009-0638-5
Publication status	Published - 2009 Dec 1
Externally published	Yes

Keywords

Dendritic cells
E-FABP
Immunohistochemistry
M cells
Mouse
Peyer's patch

ASJC Scopus subject areas

Histology
Molecular Biology
Medical Laboratory Technology
Cell Biology

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Suzuki, R., Nourani, M. R., Saino-Saito, S., Abe, H., Nochi, T., Kiyono, H., Spener, F., Kondo, H., & Owada, Y. (2009). Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine. Histochemistry and Cell Biology, 132(6), 577-584. https://doi.org/10.1007/s00418-009-0638-5

Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine. / Suzuki, Ryoji; Nourani, Mohammad Reza; Saino-Saito, Sachiko; Abe, Hiroshi; Nochi, Tomonori; Kiyono, Hiroshi; Spener, Friedrich; Kondo, Hisatake; Owada, Yuji.

In: Histochemistry and Cell Biology, Vol. 132, No. 6, 01.12.2009, p. 577-584.

Research output: Contribution to journal › Article › peer-review

Suzuki, R, Nourani, MR, Saino-Saito, S, Abe, H, Nochi, T, Kiyono, H, Spener, F, Kondo, H & Owada, Y 2009, 'Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine', Histochemistry and Cell Biology, vol. 132, no. 6, pp. 577-584. https://doi.org/10.1007/s00418-009-0638-5

Suzuki, Ryoji ; Nourani, Mohammad Reza ; Saino-Saito, Sachiko ; Abe, Hiroshi ; Nochi, Tomonori ; Kiyono, Hiroshi ; Spener, Friedrich ; Kondo, Hisatake ; Owada, Yuji. / Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine. In: Histochemistry and Cell Biology. 2009 ; Vol. 132, No. 6. pp. 577-584.

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abstract = "Fatty acid binding protein of epidermal type (E-FABP) was expressed/localized in most, if not all, populations of the dendritic cells in the subepithelial domes, follicles and interfollicular regions of Peyer's patches and presumptive macrophages in their germinal centers, and all M cells in the follicle-associated epithelium of mouse intestine. The immunoreactivity in both of the cell populations makes it easy to recognize the accumulation of DCs in the subepithelial domes in close proximity to the base of M cells, which is essential for luminal antigens to be transported to Peyer's patches. E-FABP may play some important roles in the mucosal immune reaction through Peyer's patches and associated structures.",

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AU - Abe, Hiroshi

AU - Nochi, Tomonori

AU - Kiyono, Hiroshi

AU - Spener, Friedrich

AU - Kondo, Hisatake

AU - Owada, Yuji

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Localization of fatty acid binding protein of epidermal type common to dendritic cells and presumptive macrophages in Peyer's patches and epithelial M cells of mouse intestine

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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