Local redox cycling-based electrochemical chip devicefor high-throughput assay toward evaluating embryoid bodies

Kosuke Ino, Taku Nishijo, Yusuke Kanno, Hitoshi Shiku, Tomokazu Matsue

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have previously developed a local redox cycling-based electrochemical (LRC-EC) chip device to achieve high-throughput electrochemical detection for cell analysis. In the device, two arrays of band microelectrodes are arranged orthogonally to fabricate an n×n array of crossing points with only n+n external bonding pads. The electrochemical signal at the individual crossing point can be obtained by inducing local redox cycling at the desired crossing points. By using the system, 256 electrochemical sensors can be incorporated into a single chip in high density. In this study, we applied the LRC-EC system to evaluate three-dimensional (3D) culture cells.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1345-1347
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012 Jan 1
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

Keywords

  • Cell analysis
  • Cell differentiation
  • Electrochemical detection
  • Embryoid body
  • Microelectrode array

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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