TY - GEN
T1 - Local Measurement of Instantaneous Change in Myocardial Thickness in Swine Heart During Acute Myocardial Ischemia
AU - Obara, Yu
AU - Mori, Shohei
AU - Iwai-Takano, Masumi
AU - Arakawa, Mototaka
AU - Morosawa, Susumu
AU - Shindo, Tomohiko
AU - Yamamoto, Hiroaki
AU - Yasuda, Satoshi
AU - Shimokawa, Hiroaki
AU - Kanai, Hiroshi
N1 - Funding Information:
This work was partially supported by JSPS KAKENHI JP22J10644.
Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - Ultrasound-based local strain rate (SR) measurement can detect the abnormality of the myocardial contraction owing to ischemia with high sensitivity. In the present paper, the local SR measurement using the velocity estimator based on the multifrequency phase differences was applied to the open-chest heart of swine during acute myocardial ischemia to capture the abnormality of the myocardial contraction. For the normal condition, some myocardial layers became thin during the systole even though the whole thickness of the heart wall increased. Interestingly, for the ischemic condition, the rate of the myocardial layers thinning during the systole decreased. In addition, the magnitude of thickening in the measured local SR distribution during the systole decreased in the ischemic condition. This may be caused by acute myocardial ischemia because the magnitude of thickening corresponds to the contractile force of the myocardium and it decreases in acute myocardial ischemia. The difference between the baseline and the ischemic condition was observed in the measured local SR distribution during the systole, even after only a few seconds from the occlusion of the coronary artery.
AB - Ultrasound-based local strain rate (SR) measurement can detect the abnormality of the myocardial contraction owing to ischemia with high sensitivity. In the present paper, the local SR measurement using the velocity estimator based on the multifrequency phase differences was applied to the open-chest heart of swine during acute myocardial ischemia to capture the abnormality of the myocardial contraction. For the normal condition, some myocardial layers became thin during the systole even though the whole thickness of the heart wall increased. Interestingly, for the ischemic condition, the rate of the myocardial layers thinning during the systole decreased. In addition, the magnitude of thickening in the measured local SR distribution during the systole decreased in the ischemic condition. This may be caused by acute myocardial ischemia because the magnitude of thickening corresponds to the contractile force of the myocardium and it decreases in acute myocardial ischemia. The difference between the baseline and the ischemic condition was observed in the measured local SR distribution during the systole, even after only a few seconds from the occlusion of the coronary artery.
KW - Acute myocardial ischemia
KW - local strain rate measurement
KW - multifrequency phase differences
KW - multilayer strain rate measurement
KW - myocardial contraction
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U2 - 10.1109/IUS54386.2022.9958249
DO - 10.1109/IUS54386.2022.9958249
M3 - Conference contribution
AN - SCOPUS:85143786185
T3 - IEEE International Ultrasonics Symposium, IUS
BT - IUS 2022 - IEEE International Ultrasonics Symposium
PB - IEEE Computer Society
T2 - 2022 IEEE International Ultrasonics Symposium, IUS 2022
Y2 - 10 October 2022 through 13 October 2022
ER -