Lipopolysaccharide stimulates histamine-forming enzyme (histidine decarboxylase) activity in murine dental pulp and gingiva

N. Shoji, A. Yoshida, Z. Yu, Y. Endo, T. Sasano

Research output: Contribution to journalReview articlepeer-review

Abstract

The activities of the histamine-forming enzyme, histidine decarboxylase (HDC), were measured in the dental pulp, gingiva, ear skin and liver in mice, following an intravenous injection of lipopolysaccharide (LPS). LPS induced a remarkable increase in the HDC activity in the dental pulp and the gingiva. These results suggest that the newly formed histamine produced by the induced HDC could be involved in formation of pulpitis or gingivitis (periodontits).

Original languageEnglish
Pages (from-to)207-208
Number of pages2
JournalInternational Congress Series
Volume1284
DOIs
Publication statusPublished - 2005 Sept

Keywords

  • Dental pulp and gingiva
  • Histamine
  • Histidine decarboxylase (HDC)
  • Lipopolysaccharide
  • Mouse

ASJC Scopus subject areas

  • Medicine(all)

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