The light-addressable potentiometric sensor (LAPS) represents a versatile platform for chemical and biosensing. Thanks to the light addressability, the flat sensor surface of a LAPS can be flexibly divided into areas or pixels, each functioning as an independent sensor that can be modified with various sensing materials for measuring different ions or molecules. Since it first appeared in the late 1980s, it has been applied to various cells and biological samples, driven by technological developments. In this short review, the principles of a LAPS and its variants are briefly described focusing on recent trends and applications to cells and biosensing.
- Amplitude-mode LAPS
- Cell monitoring
- Light-addressable potentiometric sensor (LAPS)
- Phase-mode LAPS
- Scanning photoinduced impedance microscopy (SPIM)
ASJC Scopus subject areas
- Analytical Chemistry