TY - JOUR
T1 - Light-addressable potentiometric sensors for cell monitoring and biosensing
AU - Yoshinobu, Tatsuo
AU - Schöning, Michael J.
N1 - Funding Information:
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. The authors would like to thank H. Iken for technical assistance (adaptation of figures and table).
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/8
Y1 - 2021/8
N2 - The light-addressable potentiometric sensor (LAPS) represents a versatile platform for chemical and biosensing. Thanks to the light addressability, the flat sensor surface of a LAPS can be flexibly divided into areas or pixels, each functioning as an independent sensor that can be modified with various sensing materials for measuring different ions or molecules. Since it first appeared in the late 1980s, it has been applied to various cells and biological samples, driven by technological developments. In this short review, the principles of a LAPS and its variants are briefly described focusing on recent trends and applications to cells and biosensing.
AB - The light-addressable potentiometric sensor (LAPS) represents a versatile platform for chemical and biosensing. Thanks to the light addressability, the flat sensor surface of a LAPS can be flexibly divided into areas or pixels, each functioning as an independent sensor that can be modified with various sensing materials for measuring different ions or molecules. Since it first appeared in the late 1980s, it has been applied to various cells and biological samples, driven by technological developments. In this short review, the principles of a LAPS and its variants are briefly described focusing on recent trends and applications to cells and biosensing.
KW - Amplitude-mode LAPS
KW - Biosensing
KW - Cell monitoring
KW - Light-addressable potentiometric sensor (LAPS)
KW - Phase-mode LAPS
KW - Scanning photoinduced impedance microscopy (SPIM)
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U2 - 10.1016/j.coelec.2021.100727
DO - 10.1016/j.coelec.2021.100727
M3 - Review article
AN - SCOPUS:85105461569
VL - 28
JO - Current Opinion in Electrochemistry
JF - Current Opinion in Electrochemistry
SN - 2451-9103
M1 - 100727
ER -