Abstract
A light-addressable potentiometric sensor (LAPS) is a chemical sensor based on the field effect in semiconductor. The width of the space-charge layer at the insulator-semiconductor interface responds to the interfacial potential on the sensing surface, which is a function of the analyte concentration. The variation of the capacitance of the space-charge layer is read out in the form of a photocurrent induced by a light probe. This light-addressability allows spatially resolved measurements of the analyte concentration. The article summarizes various aspects of the LAPS, such as the measurement setup, principle of operation, visualization of analyte concentration, as well as visualization of impedance in the scanning photoinduced impedance microscopy (SPIM) mode, spatial and temporal resolutions, functionalization of the sensing surface, and applications.
| Original language | English |
|---|---|
| Title of host publication | Encyclopedia of Interfacial Chemistry |
| Subtitle of host publication | Surface Science and Electrochemistry |
| Publisher | Elsevier |
| Pages | 295-308 |
| Number of pages | 14 |
| ISBN (Electronic) | 9780128098943 |
| ISBN (Print) | 9780128097397 |
| DOIs | |
| Publication status | Published - 2018 Jan 1 |
Keywords
- Bioimaging
- Biosensor
- Chemical imaging sensor
- Chemical sensor
- DNA
- EIS
- Electrolyte-insulator-semiconductor
- Enzyme
- Field-effect transistor
- ISFET
- Ion-sensitive field-effect transistor
- LAPS
- Light-addressable potentiometric sensor
- SPIM
- Scanning photoinduced impedance microscopy
- pH-imaging sensor
ASJC Scopus subject areas
- Chemistry(all)