Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging

M. J. Schöning, Torsten Wagner, A. Poghossian, K. I. Miyamoto, Carl Frederik Benedikt Werner, S. Krause, T. Yoshinobu

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


A light-addressable potentiometric sensor (LAPS) is a chemical sensor based on the field effect in semiconductor. The width of the space-charge layer at the insulator-semiconductor interface responds to the interfacial potential on the sensing surface, which is a function of the analyte concentration. The variation of the capacitance of the space-charge layer is read out in the form of a photocurrent induced by a light probe. This light-addressability allows spatially resolved measurements of the analyte concentration. The article summarizes various aspects of the LAPS, such as the measurement setup, principle of operation, visualization of analyte concentration, as well as visualization of impedance in the scanning photoinduced impedance microscopy (SPIM) mode, spatial and temporal resolutions, functionalization of the sensing surface, and applications.

Original languageEnglish
Title of host publicationEncyclopedia of Interfacial Chemistry
Subtitle of host publicationSurface Science and Electrochemistry
Number of pages14
ISBN (Electronic)9780128098943
ISBN (Print)9780128097397
Publication statusPublished - 2018 Jan 1


  • Bioimaging
  • Biosensor
  • Chemical imaging sensor
  • Chemical sensor
  • DNA
  • EIS
  • Electrolyte-insulator-semiconductor
  • Enzyme
  • Field-effect transistor
  • Ion-sensitive field-effect transistor
  • LAPS
  • Light-addressable potentiometric sensor
  • SPIM
  • Scanning photoinduced impedance microscopy
  • pH-imaging sensor

ASJC Scopus subject areas

  • Chemistry(all)


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