Large volume coagulation utilizing multiple cavitation clouds generated by array transducer driven by 32 channel drive circuits

Kotaro Nakamura, Ayumu Asai, Hiroshi Sasaki, Shin Yoshizawa, Shin Ichiro Umemura

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

High-intensity focused ultrasound (HIFU) treatment is a noninvasive treatment, in which focused ultrasound is generated outside the body and coagulates a diseased tissue. The advantage of this method is minimal physical and mental stress to the patient, and the disadvantage is the long treatment time caused by the smallness of the therapeutic volume by a single exposure. To improve the efficiency and shorten the treatment time, we are focusing attention on utilizing cavitation bubbles. The generated microbubbles can convert the acoustic energy into heat with a high efficiency. In this study, using the class D amplifiers, which we have developed, to drive the array transducer, we demonstrate a new method to coagulate a large volume by a single HIFU exposure through generating cavitation bubbles distributing in a large volume and vibrating all of them. As a result, the coagulated volume by the proposed method was 1.71 times as large as that of the conventional method.

Original languageEnglish
Article number07HF10
JournalJapanese journal of applied physics
Volume52
Issue number7 PART 2
DOIs
Publication statusPublished - 2013 Jul 1

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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